Over 100,000 Avandia users have reported stroke, heart disease, or heart failure. Because of those known hazards, in 2010 the FDA restricted Avandia to Type 2 diabetics who could not control their blood sugar with other medications. The FDA removed that restriction in 2013; but other drugs in the same class of drugs as Avandia have been removed from the market because they pose serious health risks.
Avandia can also cause moderate side effects, including edema (swelling), yellowing eyes or skin, impaired vision due to swelling behind the eyes, abdominal pain, nausea or vomiting, shortness of breath, and dark urine.